What is the likely cause of persistent non-breathing in a patient hours after a procedure?

The persistence of non-breathing in a patient several hours after a procedure could indeed be attributed to atypical pseudocholinesterase deficiency. This condition affects the metabolism of certain muscle relaxants, particularly succinylcholine, which is often utilized during surgical procedures for its rapid onset and short duration of action. In patients with atypical pseudocholinesterase deficiency, the duration of neuromuscular blockade can be prolonged, leading to insufficient respiratory muscle function and possible respiratory failure.

While airway obstruction is a common concern post-operatively and could also lead to non-breathing, the specific mention of persistence hours after a procedure points more towards neuromuscular factors rather than an anatomical obstruction. Severe pain can affect breathing to some extent, but it typically does not result in a complete cessation of breath. Fatigue from anesthesia can contribute to a reduction in respiratory effort, but it is unlikely to account for a total failure to breathe. Thus, atypical pseudocholinesterase deficiency stands out as a direct and significant cause of persistent non-breathing under the circumstances described.