In the context of lip lesions, which feature suggests a keratoacanthoma?

Keratoacanthoma is characterized by a distinctive growth pattern that typically includes a central keratin-filled crater or "cheesy center." This feature distinguishes it from other lip lesions, such as squamous cell carcinoma or basal cell carcinoma, which may present differently. The keratoacanthoma often starts as a small nodule that grows rapidly and eventually evolves, leading to the formation of this central crater that fills with keratin.

The presence of this cheesy center is a key histopathological feature and is indicative of the keratinization seen in this type of lesion. The rapid growth and other characteristics may be present in different types of lesions, but the central keratin-filled surface is particularly unique to keratoacanthoma and serves as a significant diagnostic criterion.