In restrictive lung disease, which pulmonary function tests are typically affected?

In restrictive lung disease, pulmonary function tests commonly show a decrease in various measures, primarily due to reduced lung volume. This reflects the impaired ability of the lungs to expand fully, which is characteristic of restrictive conditions.

Key pulmonary function tests that are typically affected include Forced Vital Capacity (FVC) and Total Lung Capacity (TLC). In restrictive lung disease, both FVC and TLC are often decreased because the lungs cannot accommodate the normal airflow and volume due to stiffness or limited expansion. The reductions in these measurements indicate that less air can be inhaled into the lungs.

In addition, while the Forced Expiratory Volume in one second (FEV1) may sometimes be reduced, the FEV1/FVC ratio remains normal or may even be increased, distinguishing restrictive lung disease from obstructive disorders where FEV1 is disproportionately lower than FVC.

Thus, marking a decrease in pulmonary function measurements accurately represents the physiological changes seen in restrictive lung disease. This understanding is crucial for diagnosing and managing such conditions effectively.